RESEARCH AWARD RECIPIENTS

2024 RESEARCH AWARD RECIPIENTS

Spring 2024 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

The Role of MMP-11 in Inverted Papilloma Migration and Transformation
Kush Panara, Tan Li Hui, Deepa Keshari, Charles Tong, Jennifer Douglas, James Palmer, Nithin Adappa, Noam Cohen, Michael Kohanski
University of Pennsylvania

CLINICAL SCIENCE RESEARCH AWARD.

In-office oxymetazoline as a predictor of turbinate reduction surgery outcome: objective support from a prospective, single-blinded, computational fluid dynamics study
Zachary Root, Thomas Lepley, Zhenxing Wu, Aspen Schneller, Robbie Chapman, Veronica Formanek, Kathleen Kelly, Bradley Otto, Kai Zhao
Ohio State University

Fall 2024 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells
Dawn Bravo, S Vaidyanathan, J Baker, …Z Sellers, T Desai, M Porteus, Jayakar Nayak
Stanford University School of Medicine

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

The AI-DIP Study: Automated Machine Learning for Inverted Papilloma versus Squamous Cell Carcinoma
Farideh Hosseinzadeh, George Liu, Esmond Tsai… Zara Patel
Stanford University School of Medicine

SHIKANI INTERNATIONAL AWARD

Protease-activated receptor 2 activates IL-13Rα1 in eosinophilic chronic rhinosinusitis via SPI-1
En-Chih Liao, Huai-Pao Lee, Ching-Chih Lee
Tri-Service General 16 Hospital, Taipei, Taiwan

2023 RESEARCH AWARD RECIPIENTS

Spring 2023 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Effects of diesel exhaust particulates on sinonasal epithelia
Jaime Pena Garcia, Daniel Skinner, Timothy Norwood, Natalie Dorin, Dong-Jin Lim, Shaoyan Zhang, Jessica Grayson, Steven Rowe, Guillermo Tearney, Bradford Woodworth, Do-Yeon Cho
University of Alabama at Birmingham

CLINICAL SCIENCE RESEARCH AWARD

Fractional exhaled nitric oxide levels correlate with sinus mucus cytokines in patients with chronic rhinosinusitis
Sophie Yu, Simon Chiang, Regan Bergmark, Alice Maxfield, Rachel Roditi, Kathleen Buchheit, Marie Lundberg, Margaret Mitchell, and Stella Lee
Brigham and Women’s Hospital, Harvard Medical School

Fall 2023 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

An Eosinophil Peroxidase Activity Assay Accurately Predicts Eosinophilic Chronic Rhinosinusitis
Kristine A. Smith, MD, Amarbir S. Gill, MD, Chelsea E. Pollard, BS, Jorgen S. Sumsion, BS, Hedieh Saffari, PhD, Shaelene Ashby, PhD,a Benjamin L. Witt, MD, Paige A. Shipman, BS, David A. Gabrielsen, MD, Michael T. Yim, MD,Joshua M. Levy, MD, MPH, MSc, Gretchen M. Oakley, MD, Richard R. Orlandi, MD a Gerald J. Gleich, MD, Jeremiah A. Alt, MD, PhD, and Abigail Pulsipher, PhD
University of Utah, Louisiana State University, Emory Univ Sch Medicine

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

Revision sinus surgery immediately prior to dupilumab therapy: A real-world study of molecular and cellular features.
Abdul Rahman Alenezi, Kathleen Kelly, Heather M. Kulaga, Abigail Gaffar, Amy Smith, Hsin-Tzu Keng, and Andrew Lane
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine

SHIKANI INTERNATIONAL AWARD

Multiple Instance Learning for Eosinophil Qualification of Sinonasal Histopathology Images: A Hierarchical Determination on Whole Slide Images
Yen-chi Hsu, Kao-Tsung Lin, Min-Sui Lee, Te-Huei Yeh, Yi-Tsen Lin
Department of Otolaryngology and Computer Science/Information Engineering, National Taiwan University

2022 RESEARCH AWARD RECIPIENTS

Spring 2022 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers
Tsuguhisa Nakayama
Stanford University

CLINICAL SCIENCE RESEARCH AWARD

A comparative analysis of endoscopic sinus surgery versus biologics for treatment of CRSwNP
Amar Migliani, MD
Medical University of South Carolina

Fall 2022 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Hypoxia-induced CFTR dysfunction is a universal mechanism underlying reduced mucociliary transport in sinusitis
Do-Yeon Cho; Shaoyan Zhang; T. Graham Norwood, Daniel Skinner; Tonja A. Hollis; Marie L. Ehrhardt;Dong-Jin Lim; Jessica W. Grayson; Ahmed Lazrak, Sadis Matalon; Steven M. Rowe; Bradford A. Woodworth
Depts OLHNS, Medicine, Anesthesiology University of Alabama at Birmingham Gregory Fleming James Cystic Fibrosis Research Center

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

Orbital Resection by Intranasal Technique (ORBIT): A new staging system for endoscopically resectable primary orbital tumors
Aria Jafari, Nithin D Adappa, Vincent J Anagnos, Raewyn G Campbell, Paolo Castelnuovo, Ara Chalian, Christopher B Chambers, Chandala Chitguppi, et al.
Multiple institutions from the USA, Australia, Italy, Beijing, Kuala Lumpur

2021 RESEARCH AWARD RECIPIENTS

Spring 2021 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Inflammatory Heterogeneity in Aspirin Exacerbated Respiratory Disease
W. Scott
Vanderbilt University Medical Center

CLINICAL SCIENCE RESEARCH AWARD

Chronic particulate matter air pollution exposure is associated with anosmia: A Case:Control Study
Nicholas R. Rowan, MD
Johns Hopkins University School of Medicine

Fall 2021 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Cystatin-Induced Coagulation and Fibrinolysis Pathway Derangements in a Murine Model of CRSwNP
Workman, Alan, Angela Nocera, Mansoor Amiji, Benjamin Bleier.
Massachusetts Eye and Ear, Harvard Medical School

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

Long-acting implantable corticosteroid matrix for chronic rhinosinusitis: Results of LANTERN Phase 2 randomized controlled study
Cervin, Anders, Joanne Rimmer, Agnieszka Wrobel, Yogen Abelak, Lindsay Brayton, Yina Kuang
University of Queensland

2020 RESEARCH AWARD RECIPIENTS

Spring 2020 (ARS at COSM)

MEETING CANCELLED DUE TO PANDEMIC

Fall 2020 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

DMBT1 is the endogenous carrier ligand for eosinophil death receptor Siglec-8 in nasal polyps
Hyun Sil Lee
Johns Hopkins University School of Medicine

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

Effect of systemic steroids on long-term post-operative sinonasal and quality of life and inflammatory biomarkers: A randomized clinical trial
Sarina K. Mueller
Massachussetts Eye & Ear Infirmary

2019 RESEARCH AWARD RECIPIENTS

Spring 2019 (Rhinoworld)

BASIC SCIENCE RESEARCH AWARD

Nasal polyp 15-lipoxygenase 1 promotes CCL26/Eotaxin3 expression through ERK activation
Zhipeng Li
University of Pittsburgh

CLINICAL SCIENCE RESEARCH AWARD

Socioeconomic status impacts postoperative productivity loss and health utility changes in refractory CRS
Daniel Beswick, MD
University of Colorado

Fall 2019 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Highly Efficient Repair of the Delta-F508 Mutation in Airway Stem Cells of Cystic Fibrosis Patients with Functional Rescue of the Differentiated Epithelia
Sriram Vaidyanathan
Stanford Univeristy

2018 RESEARCH AWARD RECIPIENTS

Spring 2018 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Nitric oxide-releasing microparticles as a potent antimicrobial therapeutic against chronic rhinosinusitis bacterial isolates
Waleed Abuzeid, MD
Albert Einstein

CLINICAL SCIENCE RESEARCH AWARD

Total Intravenous Anesthesia Improves Intraoperative Visualization During Surgery for High-Grade Chronic Rhinosinusitis: A Double-Blind Randomized Controlled Trial
Jacob Brunner, MD
Tulane University

Fall 2018 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Translating Transcription- Proteomics in CRSwNP Reveals Significant Discordance with mRNA Expression
Alan Workman, MD
Massachusetts Eye and Ear Infirmary

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

Artificially induced smell through trans-ethmoid electrical stimulation of the olfactory bulb
Eric Holbrook, MD
Massachusetts Eye and Ear Infirmary

2017 RESEARCH AWARD RECIPIENTS

Spring 2017 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Assessment of acquired mucociliary clearance defects using micro-optical coherence tomography
Kiranya Tiperneni, MD
University of Alabama at Birmingham

CLINICAL SCIENCE RESEARCH AWARD

Defining the minimal clinically important difference for olfactory outcomes in the surgical treatment of chronic rhinosinusitis
Joshua Levy, MD PhD
Emory University

Fall 2017 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Development of Non-Invasive Liquid Biopsy of Chronic Rhinosinusitis with Nasal Polyps Using Mucus Derived Exosomal Proteomics
Sarina Mueller, MD
Massachusetts Eye and Ear Infirmary

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

Olfactory Dysfunction Predicts Subsequent Dementia in Older US Adults
Dara Adams, MD
The University of Chicago

2016 RESEARCH AWARD RECIPIENTS

Spring 2016 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Secreted P-glycoprotein is a Non-Invasive Biomarker of Chronic Rhinosinusitis
Angela Nocera, MD
Massachusetts Eye and Ear Infirmary

CLINICAL SCIENCE RESEARCH AWARD

The ENS6Q: A validated 6-item questionnaire as a diagnostic aid for empty nose syndrome
Nathalia Velasquez, MD
Stanford University

Fall 2016 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Tolerance and Pharmacokinetics of a Ciprofloxacin-coated Sinus Stent in a Preclinical Model
Do-Yeon Cho, MD
University of Alabama at Birmingham

MAURICE COTTLE CLINICAL SCIENCE RESEARCH AWARD

No award.

2015 RESEARCH AWARD RECIPIENTS

Spring 2015 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Staphylococcus aureus triggers nitric oxide production in human upper airway epithelium
Ryan Carey, BSE
University of Pennsylvania

CLINICAL SCIENCE RESEARCH AWARD

A novel treatment adjunct for asprin exacerbated respiratory disease: A low salicylate diet. A multi-center randomized control cross-over trial
Smriti Nayan, MD
McMaster University, Canada

Fall 2015 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

TNF-α mediated inflammation in chronic rhinosinusitis due to differential expression of type 1 and type 2 TNF- α receptors
Ping Li, MD

CLINICAL SCIENCE RESEARCH AWARD

Cost utility analysis of endoscopic sinus surgery for chronic rhinosinusitis
George Scangas, MD
Massachusetts Eye and Ear Infirmary

2014 RESEARCH AWARD RECIPIENTS

Spring 2014 (ARS at COSM)

BASIC SCIENCE RESEARCH AWARD

Sinus microbiota in chronic rhinosinusitis
Vijay Ramakrishnan, MD
University of Colorado

CLINICAL SCIENCE RESEARCH AWARD

Cost-effectiveness analysis of medical therapy versus surgery for chronic rhinosinusitis
Evan Walgama, MD
University of Texas Southwestern

Fall 2014 (Annual Meeting)

BASIC SCIENCE RESEARCH AWARD

Sinus instillation of Lactobacillus sakei moderates Pseudomonas aeruginosa infection and increases airway microbiome resilience in a murine model.
Emily Cope, MD

CLINICAL SCIENCE RESEARCH AWARD

A randomized, controlled, blinded study of bioabsorbable steroid-eluding sinus implants for in-office treatment of recurrent sinonasal polyposis.
Joseph Han, MD
Eastern Virginia Medical School

2013 RESEARCH AWARD RECIPIENTS

Spring 2013

BASIC SCIENCE RESEARCH AWARD

IL-4 and IL-13 compromise the sinonasal epithelial barrier and perturb intercellular junction protein expression
Sarah Wise, MD

CLINICAL SCIENCE RESEARCH AWARD

A systematic review and meta-analysis of asthma outcomes following endoscopic sinus surgery for chronic rhinosinusitis
Rishi Vashishta, MD

Fall 2013 (Annual Meeting)

CLINICAL SCIENCE RESEARCH AWARD

Steroid-eluting sinus implant for in-office treatment of recurrent nasal polyposis: A prospective, multi-center study.
Fracois Lavigne, MD

BASIC SCIENCE RESEARCH AWARD

Probiotic manipulation of the chronic rhinosinusitis microbiome.
Edward Cleland, MD

2012 RESEARCH AWARD RECIPIENTS

Spring 2012

BASIC SCIENCE RESEARCH AWARD

Epithelial Permeability Alterations in an In Vitro Air-Liquid Interface Model of Allergic Fungal Rhinosinusitis
Kyle A. Den Beste, B.S.

CLINICAL SCIENCE RESEARCH AWARD

Quality-of-Life Outcomes Following Multiple Revision Endoscopic Sinus Surgery
John D. Clinger, MD

Fall 2012

BASIC SCIENCE RESEARCH AWARD

Sinonasal epithelial wound resealing in an in vitro model: inhibition of wound closure with IL-4 exposure
Sarah Wise, MD

CLINICAL SCIENCE RESEARCH AWARD

Medical therapy versus surgery for chronic rhinosinusitis: A prospective, multi-institutional study with one-year follow-up
Timothy Smith, MD, MPH

2011 RESEARCH AWARD RECIPIENTS

Spring 2011

BASIC SCIENCE RESEARCH AWARD

Polyhydrated Ionogen with MgBr2 Accelerates in vitro Respiratory Epithelial Healing
Noam Cohen, MD

CLINICAL SCIENCE RESEARCH AWARD

Cost to Society of the Upfront CT Strategy versus Empiric Medical Therapy in the Diagnosis of Chronic Rhinosinusitis
Randy Leung, MD

Fall 2011

BASIC SCIENCE RESEARCH AWARD

A Blinded Randomized Controlled Trial on the Efficacy of Chitosan Gel on Ostial Stenosis Following Endoscopic Sinus Surgery
Thanh Ha, MD

COTTLE CLINICAL SCIENCE RESEARCH AWARD

The effects of nitric oxide on Staphylococcus aureus biofilm growth and its implications in chronic rhinosinusitis
Camille Jardeleza, MD

2010 RESEARCH AWARD RECIPIENTS

Spring 2010

BASIC SCIENCE RESEARCH AWARD

Presence of dendritic cells expressing Pro-TH2 is increased in AFRS
Jennifer Mulligan, MD

CLINICAL SCIENCE RESEARCH AWARD

ESS reduces antibiotic utilization in CRS
Naveen Bhandarkar, MD

Fall 2010

COTTLE CLINICAL RESEARCH AWARD

Safety and Efficacy of a Novel Bioabsorbable, Steroid Eluting Sinus Stent
Andrew Murr, MD

BASIC SCIENCE RESEARCH AWARD

Development of a sheep model for the study of fungal biofilm in rhinosinusitis: Fungal and bacterial synergy
Sam Boase, MD.

2009 RESEARCH AWARD RECIPIENTS

Spring 2009

BASIC SCIENCE RESEARCH AWARD

Treatment-recalcitrant chronic rhinosinusitis with polyps is associated with altered epithelial cell expression of interleukin-33
Andrew Lane, MD

CLINICAL SCIENCE RESEARCH AWARD

The comparative disease burden of rhinosinusitis
Neil Bhattacharyya, MD

Fall 2009

COTTLE CLINICAL RESEARCH AWARD

Efficacy of a Novel Chitosan Gel on Hemostasis and Wound Healing Following ESS
Rowan Valentine, MD

BASIC SCIENCE RESEARCH AWARD

TNF-Alpha Inhibits Olfactory Regeneration in a Transgenic Model of CRS-Associated Olfactory Loss
Justin Turner, MD, PhD

2008 RESEARCH AWARD RECIPIENTS

Spring 2008

BASIC SCIENCE RESEARCH AWARD

Reversible Loss of Neuronal Marker Protein Expression in a Transgenic Mouse Model for Sinusitis-associated Olfactory Dysfunction
Justin H. Turner, MD, PhD

CLINICAL SCIENCE RESEARCH AWARD

Construct Validation of a Low-Fidelity Endoscopic Sinus Surgery Model
R Leung MD

Fall 2008

COTTLE CLINICAL RESEARCH AWARD

Olfactory Function and Disease Severity in Chronic Rhinosinusitis
Jamie Litvack, MD

BASIC SCIENCE RESEARCH AWARD

Interleukin 1 Receptor-like 1 Gene is Associated with Chronic Rhinosinusitis
Roberto Castano, MD